Presenter: Prof. Harm-Anton Klok
Institutes of Materials and Chemical Sciences and Engineering
Ecole Polytechnique Fédérale de Lausanne (EPFL)
Topic: Surface engineering using controlled radical polymerization
Time: 3：30PM, Apr. 21st (Thursday)
Location: Conference Room B, BLDG 909-1F
Thin polymer coatings are of great importance to control the interactions of synthetic materials with other materials (lubrication, wear), the environment (corrosion) as well as biology (marine antifouling). Modern polymer science offers unprecedented opportunities to chemically engineer the properties of surfaces and interfaces. This presentation will discuss three aspects. The first part of the presentation will introduce modern controlled/”living” radical polymerization techniques and “polymer brushes” (chain-end tethered monomolecular assemblies of densely grafted polymer chains) and present the scope and possibilities of these approaches to chemically modify surfaces and interfaces. The second part of the presentation will address the need for accurate surface chemical characterization and the challenges related to the precise determination of the localization and distribution of functional groups in thin polymer films. The presentation will end with several brief showcases that illustrate the use of modern polymer science tools to develop ultrathin polymer films that possess sensory properties, which can be used to control fluid flow, to template the controlled growth of metallic or non-metallic inorganic films on complex, 3D structured substrates as well as to guide and control cell adhesion.
1.R. Barbey, L. Lavanant, D. Paripovic, N. Schüwer, C. Sugnaux, S. Tugulu, H.-A. Klok, Polymer brushes via surface-initiated controlled radical polymerization: synthesis, characterization, properties and applications, Chem. Rev. 2009, 109, 5437.
2.N. Schüwer, T. Geue, J. P. Hinestrosa, H.-A. Klok, Neutron reflectivity study on the postpolymerization modification of poly(2-hydroxyethyl methacrylate) brushes, Macromolecules 2011, 44, 6868.
3.R. Barbey, V. Laporte, S. Alnabulsi, H.-A. Klok, Postpolymerization modification of poly(glycidyl methacrylate) brushes: An XPS depth-profiling study, Macromolecules 2013, 46, 6151.
4.N. Schüwer, H.-A. Klok, A potassium-selective quartz crystal microbalance sensor based on crown-ether functionalized polymer brushes, Adv. Mater. 2010, 22, 3251.
5.C. Sugnaux, L. Lavanant, H.-A. Klok, Aqueous fabrication of pH-gated, polymer-brush-modified alumina hybrid membranes, Langmuir 2013, 29, 7325.
6.S. Desseaux, H.-A. Klok, Temperature-controlled masking/unmasking of cell-adhesive cues with poly(ethylene glycol) methacrylate based brushes, Biomacromolecules 2014, 15, 3859 – 3865.
7.S. Desseaux, H.-A. Klok, Fibroblast adhesion on ECM-derived peptide modified poly(2-hydroxyethyl methacrylate) brushes: ligand co-presentation and 3D-localization, Biomaterials 2015, 44, 24 – 35.
8.N. Fortin, H.-A. Klok, Glucose monitoring using a polymer brush modified polypropylene hollow fiber-based hydraulic flow sensor, ACS Appl. Mater. Interfaces 2015, 7, 4631 – 4640.
9.C. Sugnaux, A. Dalmau Mallorquí, J. Herriman, H.-A. Klok, A. Fontcuberta i Morral, Polymer brush guided formation of conformal, plasmonic nanoparticle-based electrodes for microwire solar cells, Adv. Funct. Mater. 2015, 25, 3958 – 3965.
Harm-Anton Klok is Full Professor at the Institutes of Materials and Chemical Sciences and Engineering at the Ecole Polytechnique Fédérale de Lausanne (EPFL) (Lausanne, Switzerland). His research interests include polymer nanomedicine as well as polymer surface and interface science.
He studied chemical technology at the University of Twente (Enschede, The Netherlands) from 1989 to 1993 and received his Ph.D. in 1997 from the University of Ulm (Germany) after working with Martin M?ller. After postdoctoral research with David N. Reinhoudt (University of Twente) and Samuel I. Stupp (University of Illinois at Urbana–Champaign, USA), he joined the Max Planck Institute for Polymer Research (Mainz, Germany) in early 1999 as a project leader in the group of Klaus Müllen. In November 2002, he was appointed to the faculty of EPFL. Since 2012 he is Director of the Institute of Materials (~ Department Head) and also directs the Molecular and Hybrid Materials Characterization Center at EPFL.
Harm-Anton Klok is recipient of the Arthur K. Doolittle Award of the American Chemical Society (2007) and is Associate Editor of the American Chemical Society journal Biomacromolecules and serves or has served on the editorial advisory board of Eur. Polym. J., J. Polym. Sci. A: Polym. Chem., Macromolecules, ACS Macro Letters as well as Macromol. Rapid Commun., Macromol. Bioscience and Chimia. He has been a Visiting Professor at the University of Bordeaux (France) and the University of Massachusetts/Amherst (USA), is a Chair Professor at the College of Chemistry, Chemical Engineering and Materials Science, Soochow University (Suzhou, China), guest professor at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences (Changchun, China), at the School of Environmental and Chemical Engineering, Shanghai University (Shanghai, China) and at the School of Materials Science and Engineering, Nanyang Technological University, Singapore and was awarded a Chinese Academy of Sciences visiting professorship for senior international scientists (Institute of Chemistry, Chinese Academy of Sciences, Beijing).