In Vitro and In Vivo Near-Infrared Photothermal Therapy of Cancer Using Polypyrrole Organic Nanoparticles
Kai Yang ,1 Huan Xu ,1 Liang Cheng ,1 Chunyang Sun ,2 Jun Wang ,2 and Zhuang Liu 1,*
1Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials Laboratory (FUNSOM), Soochow University, Suzhou, Jiangsu 215123, China
2 School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China
Poly(vinyl alcohol)-coated polypyrole, a conductive polymer that forms nanoparticles in the aqueous phase, is used as a near-infrared light-absorbing agent for photothermal therapy of cancer, obtaining excellent cancer ablation therapeutic effects in both cellular and animal experiments.