刘庄教授课题组在Advanced Materials上发表论文

发布时间:2012-02-29访问量:17设置

题目:

Multimodal Imaging Guided Photothermal Therapy using Functionalized Graphene Nanosheets Anchored with Magnetic Nanoparticles

作者:

Kai Yang ,1 Lilei Hu ,1 Xingxing Ma ,2 Shuoqi Ye ,3 Liang Cheng ,1 Xiaoze Shi ,1 Changhui Li ,3 Yonggang Li ,2 and Zhuang Liu *1

单位:

1Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices Institute of Functional Nano & Soft Materials Laboratory (FUNSOM) Soochow University, Suzhou, Jiangsu 215123, China

2Department of Radiology the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China

3Department of biomedical engineering college of engineering, Peking University, Beijing, 100871, China

摘要:

In this work, a nanoscale reduced graphene oxide–iron oxide nanoparticle (RGO–IONP) complex is noncovalently functionalized with polyethylene glycol (PEG), obtaining a RGO–IONP–PEG nanocomposite with excellent physiological stability, strong NIR optical absorbance, and superparamagnetic properties. Using this theranostic nanoprobe, in-vivo triple modal fluorescence, photoacoustic, and magnetic resonance imaging are carried out, uncovering high passive tumor targeting, which is further used for effective photothermal ablation of tumors in mice.

影响因子:

13.877

分区情况:

1




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